CHIP regulates skeletal development and postnatal bone growth
نویسندگان
چکیده
منابع مشابه
FGF signaling in the osteoprogenitor lineage non-autonomously regulates postnatal chondrocyte proliferation and skeletal growth.
Fibroblast growth factor (FGF) signaling is important for skeletal development; however, cell-specific functions, redundancy and feedback mechanisms regulating bone growth are poorly understood. FGF receptors 1 and 2 (Fgfr1 and Fgfr2) are both expressed in the osteoprogenitor lineage. Double conditional knockout mice, in which both receptors were inactivated using an osteoprogenitor-specific Cr...
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ژورنال
عنوان ژورنال: Journal of Cellular Physiology
سال: 2020
ISSN: 0021-9541,1097-4652
DOI: 10.1002/jcp.29424